The first clash of week five was an all-California affair as the 3-1 LA Rams hosted the 3-1 49ers. The NFC West rivals produced an exciting game that was settled in overtime by an Eddy Pineiro field goal. It was a surprise 26-23 win for the visitors since they were much depleted and was their first in OT since they lost the Super Bowl that way in 2024.
London hosted a game this week too, welcoming the Vikings and the Browns, the former coming from three down in the fourth quarter to win 21-17. The Cowboys condemned the Jets to a fifth straight defeat, winning 37-22 on the road, while Detroit continued to score freely, beating the Bengals 37-24.
The Patriots moved into positive territory for the season by beating the Bills 23-20 on the road to go 3-2. It was Buffalo’s first loss of the season and perhaps the first sign that New England could be a team worth watching this year. Elsewhere the Seahawks were edged out in a thriller on home soil, going down 38-35 to the Bucs, who moved to 4-1 and maintained their 100% record on the road.
NFL Week 5 Fixtures & Results
| Day* | Date | Team 1 | Score | Team 2 |
|---|---|---|---|---|
| Friday | 3rd Oct 2025 | San Francisco | 26 - 23 (OT) | Los Angeles Rams |
| Sunday | 5th Oct 2025 | Miami | 24 - 27 | Carolina |
| Sunday | 5th Oct 2025 | Detroit | 37 - 24 | Cincinnati |
| Sunday | 5th Oct 2025 | Minnesota | 21 - 17 | Cleveland |
| Sunday | 5th Oct 2025 | Las Vegas | 6 - 40 | Indianapolis |
| Sunday | 5th Oct 2025 | Washington | 27 - 10 | Los Angeles Chargers |
| Sunday | 5th Oct 2025 | New York Giants | 14 - 26 | New Orleans |
| Sunday | 5th Oct 2025 | Dallas | 37 - 22 | New York Jets |
| Sunday | 5th Oct 2025 | Denver | 21 - 17 | Philadelphia |
| Sunday | 5th Oct 2025 | Tampa Bay | 38 - 35 | Seattle |
| Sunday | 5th Oct 2025 | Tennessee | 22 - 21 | Arizona |
| Sunday | 5th Oct 2025 | Houston | 44 - 10 | Baltimore |
| Monday | 6th Oct 2025 | New England | 23 - 20 | Buffalo |
| Tuesday | 7th Oct 2025 | Kansas City | 28 - 31 | Jacksonville |
*Note - dates and times are in GMT and may show a different day to the US schedule.